Dr. Wright’s Protocol: D-Mannose And SSKI For UTI Treatment

Dr. Jonathan V. Wright was the first physician to introduce D-Mannose in clinical practice in the late 1980sin the USA and he also is extensively using SSKI for urinary tract infection treatment. He is the Medical Director of Tahoma Clinic in Tukwila, Washington (www.TahomaClinic.com and an author of  “D-Mannose and Bladder Infection: The Natural Alternative to Antibiotics” (as well as dozens of other books and articles). A graduate of Harvard University and the University of Michigan Medical School, Dr. Wright has introduced several groundbreaking natural treatments for various conditions including UTI, asthma, eczema, osteoporosis, and even some severe neurological problems.

Below is our conversation about treating chronic and acute UTI with supplements and SSKI. The interview is for informational purposes only and isn’t medical advice.

Allergy Is A Risk-Factor For UTI

Anastasia Visotsky: What makes somebody prone to UTIs?

Dr. Wright: There are many factors, but I will highlight two that are worth special mention: allergies and hormonal imbalance.

Chronic exposure to allergens shifts your body’s defense mechanism toward fighting an allergen rather than protecting you from bacteria and viruses. Therefore, if you have allergies you could be more easily prone to frequent UTIs. You might not even have a full-blown reaction requiring an EpiPen but a low-grade allergy could still be taxing your immune system.

For pediatric patients, especially, I recommend completing a full panel allergy test. Dairy is a known big food allergen and, unfortunately, is frequently dominating kids’ diets. I advise looking into allergy in every case of persistent infection with kids, whether it is a strep throat, UTI, or anything else.

Hormonal imbalance is a second hidden factor that many practitioners overlook. During menopause or before puberty, women are more prone to UTIs due to changing hormones that affect the number of Lactobacilli in their vaginas, making them more susceptible to E. coli colonization.

While little girls will outgrow this problem, older women might need hormonal supplementation. I suggest looking into natural, identical-to-human (“bio-identical”) estrogens such as estrone, estradiol, and especially estriol (always balanced with “bio-identical” progesterone).

Dr. Wright’s D-Mannose Protocol

Anastasia Visotsky: What should we know about D-Mannose protocol for UTI?

Dr. Wright: D-Mannose is well suited for children, pregnant women, diabetics. In fact, the first patient I gave D-Mannose to try was a 9-year-old girl who suffered from chronic UTIs and antibiotics were not helping her anymore.

I can’t recommend any particular brand, they all work the same way. My only recommendation is to look for pure D-Mannose, without additives, and made by a reputable brand.

Of course, you can supplement with cranberry pills but they are not as effective as D-Mannose.

For active infection, adults can try 1 teaspoon of D-Mannose dissolved in a glass of water every 2-3 hours (children aged 6-8 and under can use ½ of a teaspoon every 2-3 hours) excluding the night time unless waking up to empty the bladder (then another dose can be taken).

You should see a noticeable improvement within 24 hours but continue with the same dose for another 2 days.  

After that, a preventive dose of just one teaspoon per day can be continued. If symptoms totally resolve, there is no need to continue D-Mannose.  

If you are aware that a particular activity triggers a UTI (such as taking a tub bath, or sex), consider taking a dose before and after the activity.  

SSKI For UTI Treatment

Anastasia Visotsky: What about UTIs that are caused by other types of bacteria, not E. coli?

Dr. Wright: Since E.coli is responsible for 90% of all UTIs (but not 100%) the remainder of bacteria and fungi that cause UTI could be exterminated by taking a saturated solution of potassium iodide (SSKI).  

I suggest 15 drops in water every 3-4 hours for two days. No need to get up from sleeping to take it; the iodide stays in the bladder and keeps on killing germs. This protocol should clear any infection.

However….it tastes bad, and can (very rarely) cause an allergic reaction. Therefore, either do a culture test to confirm the type of bacteria that is causing your UTI or try D-Mannose first.

Also, remember: don’t take iodine or iodide “long-term” (more than two to three days) without advice from a physician skilled and knowledgeable in natural medicine, as too much iodine or iodide can suppress the function of the thyroid gland.

UTI & Diet

Anastasia Visotsky: Any parting words about diet beneficial for UTI prevention?

Dr. Wright: In terms of diet, the less sugar, carbs, preservatives you consume, the better.

Cranberries, blueberries and especially their juices also are useful to inhibit E. Coli adherence to the lining of the bladder and urinary tract.

Vitamin A (as vitamin A, not carotene or carotenoids) is also one key to strengthening all surface membranes including the lining of the bladder and urinary tract.

You can find more information about Dr. Wright and Tahoma Clinic at http://tahomaclinic.com/ with a link to his online store featuring unique supplements designed by Dr. Wright.  Dr. Wright authors a monthly newsletter with vital natural health info: https://greenmedicinenewsletter.com/


11 thoughts on “Dr. Wright’s Protocol: D-Mannose And SSKI For UTI Treatment”

    1. Anastasia Visotsky

      Actually, I heard both theories: that if the organisms express pili (little tiny “hands” to hold on to the bladder lining) then it could be useful to take D-Mannose. It won’t hurt to try, especially since most UTI are multimicrobial.

  1. Hi!
    Thank you so much for this website. It’s so informative and helpful.
    I’ve been battling UTI symptoms ( very sore/ aching pelvis; irritated/slight burning feeling in the urethra; greater urgency and a need to empty my bladder more) for about three and a half months. In the past, d mannose ( I use the waterfall sweet cures brand…it’s the only brand I’ve ever used. Are you familiar with it? Would you consider this an effective brand?) used to take care of it but this bout has been more stubborn. Although, d mannose alleviated 60% of my symptoms, I couldn’t kill this infection off. Plus, d mannose does cause me intestinal discomfort and a rumbling tummy ( I can never take it two days in a row) I chose to bite the bullet and went on a three day course of MACROBID ( a pill every twelve hours until I’d taken all six capsules). It was my first time on this antibiotic and, although, thankfully, I didn’t experience any negative side effects, it has not improved my symptoms which has shocked and distressed me( this is the first time an antibiotic has been ineffective for me. I took trimethoprim almost 4 1/2 years ago and that had worked but it gave me crippling nausea and horrible intestinal cramps ) I must confess that I, stupidly I can now see in hindsight, failed to completely cut out sugar while I was taking the course ( I continued to drink Fanta free every day). Could that be it? But why was there virtually no improvement ( if there was, it was negligible)? Please advise. I’m really scared. I don’t know what to do…is there any herbal remedy you can recommend? I’m severely anaemic or I’d try oil of oregano…please advise. This constantly aching pelvis and irritated spasming is driving me crazy… How does one know if they have a “complicated” infection? I read your interview with Dr. Wright and I’d try potassium iodide but I’m scared because I am genetically predisposed to hypothyroidism. I also can’t seem to find a suitable brand that ships to the UK… I’d really appreciate your help/advice. Thank you so much for your time.

    1. Anastasia Visotsky

      Hi Mary, sorry you have to go through all that! The only thing I could recommend is to go to a doctor and give them your urine for a culture test, see what will grow there. Even better, now that you are done with the antibiotics, send your urine for a broth test or any DNA-based test. Once you know what you have you can work on addressing the issue. Unfortunately, the symptoms you describe could mean many things (read: why antibiotics didn’t help) that’s why I think, the first step is to figure out the issue rather than assume you have an acute UTI and start on a variety of treatments. Hope this makes sense! Best wishes,

  2. Bridie Patterson

    Hi Anastasia,
    I am very grateful for all the advice you are providing. I have Ulcerative colitis and IC. I know I need to address my hormone imbalance and have been looking at this website for some time. Have you any knowledge of their bio identical hormone creams? Their 20-1 cream is a combination of Progesterone and Oestrogen.
    Thank you

  3. I had pelvic radiation therapy 12 months ago and a UTI (ecoli)infection every month since. I feel sick on antibiotics every month so tried d-mannose and I’m free of UTI. Is it safe to take one serving of d-mannose every evening for future prevention or is this not healthy or recommended?

  4. Hi, I’m wondering what concentration or amount of the SSKI is being referred to in Dr. Wright’s dosage recommendation. 15 drops in water yes, but how much SSKI is there per drop? I’m sure every product’s concentration is different and no particular product is being referred to here. Please help! D-mannose did not work for me as I don’t have an E-coli UTI!

    1. Anastasia Visotsky

      Hi Odette,
      Honestly, he did not mention, from how he explained it if your naturopath orders SSKI, the compounding pharmacy will probably know. In all his post he only refers to SSKI without mentioning the concentration. Sorry!

    2. You can obtain the proper SSKI by calling his Tahoma Clinic. It is called Bernard’s Solution. This type of SSKI is NOT the one available in the supplement stores. It should cost around $35.
      I found SSKI after discovering I had a Klebsiella infection… this killed it.
      Good luck!

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