While it’s tempting to jump to a conclusion and blame “bad bacteria” for all the troubles, I suggest you take a moment to appreciate the sheer multitude of the issues that could disguise themselves as a urinary tract infection or make you prone to infection.
Gaining awareness about UTI causes could drastically improve your chances of healing. Please, don’t be quick to start a “protocol” or buy a new supplement that worked for someone. Jumping to a solution without recognizing true causes will only cost you money and time.
Let’s rule out other things
In our Facebook group, we often encounter cases when UTI-like symptoms are caused by an undiagnosed yeast, BV, or pelvic pain. The pain could also be a residual inflammation that still feels like stinging, burning, or bladder ache long after acute infection is gone.
Needless to say, if your pelvic floor muscles are tight or your urethra is healing after a raging inflammatory response, no amount of antibiotics or D-mannose would do.
Urinary tract infections: causes
If, indeed, your symptoms are urinary tract infections, you have to figure out why you became prone to them.
Many think that poor hygiene is the main reason for UTI, but this is far from the truth. In most cases, your hygiene habits have little to do with your chances of developing a UTI. It’s not even about bacteria in your bladder, since we now know that even healthy people often have similar bladder bacteria as do folks prone to UTIs.
If you keep experiencing persistent chronic UTIs, bacterial biofilms might be the ones to blame.
I grouped UTI causes in 5 main “buckets” to help you to remember what to watch out for. While the list is long, it is still far from being complete. Since chronic and recurrent UTI is often a systemic problem, many things could contribute to your UTI susceptibility, but this post is an excellent start to examine your risk factors.
Misbalanced Vaginal Flora
Compromised vaginal flora is one of the most overlooked UTI causes. There is a very close link between loss of normal vaginal flora (particularly Lactobacillus species) and an increased risk of contracting a UTI.
“Wait for a second,” I hear you saying, “if UTIs happen in my bladder, what does my vagina have to do with it?”.
Unfortunately, the critical role of a healthy vagina in UTI prevention is not common knowledge. The fact is E.coli bacteria (that cause 90% of all UTIs and live in your lower intestines) ascend from your anal region toward your urethra. On the way toward your urethra, pathogenic bacteria pass through your vagina. If your vaginal flora is healthy, the bad guys will struggle to survive. However, if vaginal flora is compromised, E.coli bacteria will multiply and continue climbing up toward your urethra and, eventually, the bladder.
A healthy vaginal flora consists of predominantly Lactobacillus species. Those tiny good bacteria are on your side. Every day, researchers find more ways to help our bodies function and how the lack of those bacteria could lead to various misalignments.
For example, scientists speculate that:
- Lactobacillus species might help to maintain the low pH of the genital area.
- Produce hydrogen peroxide.
- Hinder the growth of E. coli.
- Help to down-regulate inflammatory reactions caused by E. coli.
In plain words, not only do good bacteria make it hard for E. coli bacteria to grow and populate your genitals, but they also reduce inflammation and support healthy pH of your vagina.
However, it is easy to affect the wellbeing of your well-meaning bacteria. Those tiny warriors are kind of fragile, and plenty of things can disrupt their ability to grow and protect you.
Here are some factors that can affect your vaginal flora, and therefore, it could be considered risk factors for UTI.
Condoms with spermicide
The most popular spermicide used for condoms is Nonoxynol-9. This chemical is known to disrupt your vaginal flora and to suppress the growth of beneficial Lactobacilli.
No wonder many think that condoms cause a UTI when it’s the spermicide that works against you. If you can, use condoms without spermicide to avoid this UTI risk-factor.
Plenty of other contraceptive products use Nonoxynol-9, such as contraceptive films, sponges, suppositories, creams, and tablets. You want to avoid these as much as you can. If in doubt, make sure to read the label.
I used to get a yeast infection every time after using a lubricant. And no wonder, lubricants can also be a contributing factor of UTI causes.
Avoid lubricants with Glycerin or Sorbitol on their ingredient list since these tend to feed your pathogenic bacteria and yeast, which then suppresses the growth of the protective Lactobacilli.
Antibiotics are supposed to cure, not cause a UTI, right? That’s true; they will help you to get rid of acute infection but, in doing so, could handicap your natural defenses.
You see, when an antibiotic is busy killing E.coli and other harmful bacteria that caused your UTI, your good bacteria also suffer. As you can expect, you find yourself in a vicious cycle: you need antibiotics to fight an acute infection, but after the fight is over, your vagina is no longer protected against pathogenic bacteria. That’s why ladies who suffer from recurrent UTIs could be most vulnerable to contract a UTI again within a week after antibiotic treatment.
This factor seems to affect all aspects of our health. Whatever health problem you have, you can link some of them to stress more often than not. Not only do you feel nervous and anxious, but your bacteria suffer too.
Some studies show that stress decreases the number of Lactobacillus species that live and prosper in your body (as reported by Femke Lutgendorff et al. in the June 2008 issue of Current Molecular Medicine). Take a deep breath and make yourself a chamomile tea, go for a walk, and count your blessings. More importantly, include special probiotics in your diet so you can lend a helping hand to your Lactobacilli population.
Your friendly bacteria are picky eaters. Also, they like healthy food and lots of fiber. They also need a variety of fiber, so drinking lots of psyllium husk won’t be enough. Stock up on various veggies and fruits, exclude processed food and sugars, and add a nice prebiotic blend to your diet.
Lack of estrogen
Women don’t have it easy: periods, cramps, UTIs, babies, and menopause! Menopause frequently comes with an increased risk of UTI due to lack of estrogen that, in turn, disbalances their vaginal flora. On top of this, the lack of estrogen leads to thinning the protective layer of the vaginal walls. It makes it easier for pathogenic bacteria to hide in the vagina.
Of course, change in your hormones could happen at any age, but chances are higher that you’ll need estrogen supplementation once you are older.
Studies show that when women are given estrogen hormones, their vaginal Lactobacillus flora increased, and therefore, hormonal changes could be counted as one of the important UTI causes.
Increased number of opportunistic bacteria
More than 80% of all UTIs in the world are caused by opportunistic bacteria, such as Escherichia coli bacteria (E. coli) that reside in your gut. Therefore, we can speculate that higher E. coli concentration can lead to increased chances of contracting a UTI.
Constipation is not only unpleasant, but it is also a symptom of a bigger problem. The thing is, your gut is similar to your vagina and is also populated by millions of bacteria.
Your body needs these bacteria to aid in various vital functions such as the breakdown of food into absorbable nutrients, the stimulation of the host immune system to prevent the growth of pathogenic bacteria, and to produce a great variety of biologically important compounds. For example, E. coli bacteria, when contained in the lower gut, help produce vitamin K.
However, constipation could be a sign of an alteration in your microbiome. Some bacteria species reduce their activity, while others continue to strive. Unfortunately, the bacteria that continue to grow are mostly the ones that could become pathogenic if they get into your urethra.
So constipation is a risk factor for UTI because it could increase the number of harmful bacteria in your stool and, therefore, around your anus. On top of this, constipation might also cause internal pressure on your bladder, obstructing it and making it more difficult to empty the bladder.
Bottom line, eat your veggies and exercise to prevent UTIs caused by constipation.
Unless this is your very first UTI, you must have heard a million times that it is essential to stay hydrated to prevent urinary tract infections. Why? Well, gone are days when scientists thought that your bladder is sterile. It is not. As everywhere else, there are dozens of various strains of bacteria in your bladder, doing whatever they need to do to keep you healthy. However, pathogenic bacteria enter your bladder from time to time as well. All those bacteria live their busy lives and multiply.
If there is no fresh urine that frequently washes through your bladder, the old urine harbors growing pathogenic bacteria, causing a UTI.
In some rare cases, bacteria could be leaking from your gut straight into your bladder. This condition is known as Vesicoenteric fistulae (or enterovesical or intestinovesical fistulae). This is an opening between the bowel and the bladder that could happen due to surgery, accident, cancer, or abnormal anatomic development of an embryo. However, most frequently, due to physiological differences, this is observed in men rather than in women.
The inability to fully void your bladder is one of the main reasons for UTIs. As described above, when old urine remains in your bladder, it allows bacteria to grow. Anything that causes urine to stay in the bladder for a prolonged period of time can increase your chances of developing a UTI.
Anyone with an abnormality of the urinary tract that obstructs urine flow—a kidney stone or enlarged prostate, for example—is at risk for a UTI.
Therefore, these are five UTI causes related to bladder obstruction:
Spinal cord injuries or other nerve damage around the bladder
Spinal cord injuries can be of varying degrees. In some cases, an injury can result in a decreased ability to feel the urge to urinate, leaving urine in the bladder for too long. Other patients might not initiate the urination on their own at need a catheter to empty the bladder, which might also lead to urine staying in the bladder for more extended periods.
Kidney and bladder stones
Stones obstruct not only normal urine flow but also damage protective bladder lining, allowing for pathogenic bacteria to hide and prosper, causing recurrent UTIs. On top of that, bacteria can create their colonies on the stones’ surface, called biofilms that are often impossible to eradicate with antibiotics.
Some folks are born with a deformity that could make urine flow backward (aka Vesicoureteral reflux (VUR). If a child is diagnosed with recurrent UTIs, the doctors would most likely check with ultrasound equipment if their kidneys function well.
Bladder and urethra scarring, blood clots
The more infections you experience, the higher are your chances of developing bladder lining abnormalities. Anything but perfectly healthy bladder lining could cause recurring UTIs by providing hiding places for pathogenic bacteria and allowing for so-called embedded UTI. A bladder lining that went through numerous UTIs will be eroded and lack its protective qualities. That’s why healing your bladder is an essential step in UTI preventive strategy.
This factor is unique to men. The prostate is located close to the urethra and, if enlarged, could make it hard or even impossible to pee. If you can’t pee out your old urine, you are just asking for trouble. Moreover, if E.coli bacteria infect the prostate, they can eventually reach your bladder and cause a bloodborne UTI.
Weak bladder muscles
In this case, a patient can’t squeeze their bladder muscles strong enough to empty the bladder, always leaving old urine in the bladder. There are non-invasive tests, such as uroflowmetry, that your doctor can perform to assess your bladder muscles’ strength.
Decreased number of good bacteria in your bladder is one of the reasons harmful bacteria can grow faster. As we discussed earlier, your bladder is not sterile. Certain microbes, including beneficial ones, exist in the healthy human bladder.
Multiple factors, including diet and even your blood type, can affect your bladder flora, making it more or less prone to urinary tract infections.
These factors include:
Chronic diseases (for example, diabetes)
If you have diabetes, you are twice as likely to contract a urinary tract infection (UTI). Extra glucose in your urine drives changes in your bladder flora, making you more prone to UTIs. However, diabetes is not the only culprit. Any chronic inflammation or suppressed immune system, allergies, chronic digestion issues could contribute to your overall ability to fight infections.
Certain types of surgeries, for example, TransVaginal Mesh can be a risk factor for UTI. Any bladder surgery messes up your natural bladder microbiome and could potentially result in a UTI.
Use of instrumentation and catheters
Catheters are a known culprit of UTIs. Think of it as a bridge and also a hiding place for pathogenic bacteria in your bladder. What’s more, any instrumentation or catheters can scratch the delicate inner surface of the urethra and bladder. Even a catheter used temporarily during a surgery, or a procedure (intermittent catheter) can damage urethral or bladder lining and make it easier for bacteria to hide and proliferate.
Similar to how antibiotics affect your vaginal microbiome, they influence your bladder microbiome’s bacterial composition as well.
One could argue that bacterial biofilms in the bladder are the number one reason for chronic recurrent urinary tract infections. These are bacterial colonies that attach themselves to the bladder surface and produce protective slime to avoid antibiotics and immune system defenses. Pathogenic bacteria hide under the slime of a biofilm and are dormant during the treatment but wake up and grow after treatment. If you notice that your symptoms subside during antibiotic treatment, but a week or two later, you have an infection again, this could be due to bacterial biofilms.
Activities that transfer bacteria
In some cases, your hygiene routines can pose a greater UTI risk. I’m sure if you are an adult, you are wiping from front to back. Should we even talk about it? Nonetheless, if you ever go to a physician’s office, you are destined to hear it again.
But besides wiping, other activities can help your E. coli bacteria to “get a lift” from your anus towards your urethra and will increase the chances of contracting a UTI.
While this is RARELY the main reason, let’s cover the basics. Take your shower, do not sleep in the same underwear that you wear all day. Oh, and, of course, wipe from front to back.
Bad hygiene also means over-cleaning. Using antibacterials soaps, vaginal douching, and too frequent washing could alter your genital skin microbiome.
If your vaginal flora is compromised, E. coli can grow in your vagina. The next time you have sex, the bacteria will get much closer to your urethra, significantly increasing your UTI chances. Sex on its own doesn’t cause a UTI, but it’s a significant risk factor if your vaginal flora is compromised.
A narrow piece of material will pick up more bacteria and then slide back and forth while you move. While studies did not find conclusive evidence, many doctors recommend opting for simple cotton panties instead of thongs.
Feminine menstrual products
Just remember to change them regularly, or they could become a breeding ground for pathogenic bacteria. Blood is alkaline, and your Lactobacilli prefer an acidic environment. So do not put too much stress on your vaginal flora and change pads and tampons as frequently as possible.
On its own, anal sex or finger anal play would not cause a UTI. However, these activities bring the bacteria from inside the anal cavity to your anal region’s surface. To be safe, use a condom and discard it right away. Do not use the same condom for vaginal penetration.
Am I missing anything? Leave me a comment below and share your thoughts.