6 Worst D-MANNOSE Mistakes. D-Mannose Dose For UTI. How To Take D-Mannose

According to Dr. Wright who was the first physician to use D-Mannose in the USA in the 1980s, D-Mannose helps prevent and treat UTIs caused by E. coli bacteria. However, it’s important to note that the FDA does not support his statement and recognizes D-Mannose only as a supplement that is not intended to prevent or treat UTI.

At the same time, the treatment of UTI with D-Mannose has a solid theory behind it and some successful clinical research studies that have demonstrated D-Mannose effectiveness for UTI prevention (this one: D-Mannose is as effective as antibiotics in UTI prevention and this one). D-Mannose is also a pretty safe and has only a few manageable side-effects.

What’s D-Mannose?

D-Mannose is actually a type of sugar. But not your regular sugar (glucose), which goes with your coffee (this type would actually make your symptoms worse).

Instead, your body does not metabolize D-Mannose like other sugars. That’s why D-Mannose does not affect the blood sugar levels, and therefore is safe for the diabetics.

This is also why once you intake D-Mannose it is quickly expelled from your body in urine.

Maintaining a high concentration of D-Mannose in urine is a key way to fight an E. coli bacterial growth in your bladder.

So you might wonder why your doctor never mentioned D-Mannose, and that’s a legitimate question.

Why My Doctor Doesn’t Know About D-Mannose?

First of all, most physicians follow official treatment guidelines, otherwise, they are just asking for legal trouble.

Second, D-Mannose doesn’t always work as well as antibiotics, as it’s a natural substance and the quality, therefore, varies.

Third, clinical trials that would require a re-classification of D-Mannose as a drug are prohibitively expensive, and given that D-Mannose is naturally occurring, there is no interest on behalf of big pharma to sponsor such trials (because they can’t patent it and then return the money they borrowed to pay for such trials).

UTI Prevention Is Better Than Cure

While D-Mannose is a great supplement, it’s only one part of the solution. Do you want to prevent UTI naturally, without antibiotics? Most likely you’ll need a range of strategies to:

Key Points: How To Take D-Mannose. D-Mannose Dose For UTI. 

  • Buy D-Mannose in powder instead of capsules. One of the best “bang for the buck” options on Amazon is BulkSupplements Pure D-Mannose Powder.
  • Drink half of glass of water with your first D-Mannose dose (1 teaspoon 2-3 hours for treatment supplementation)
  • Take D-Mannose as early a possible before the infection fully develops
  • Don’t self-treat for longer than two days
  • If you have a corn allergy, here are D-Mannose options that are not made from corn: Pure Encapsulations – d-Mannose Powder.
  • Keep in mind, E. coli are responsible for 90% of all urinary tract infections, the rest could not be cured by D-Mannose.

Common Mistakes When Taking D-Mannose

#1 Common mistake: Drinking your first dose of D-Mannose with a lot of water

If you just ingested D-Mannose, wait a moment before drinking a lot of water. If you are drinking too much water right away, you are diluting the concentration of D-Mannose in your bladder, thereby cutting down its potency.

  • Take your dose with no more than half of a glass of water
  • Then wait for about 45 mins to an hour
  • After that, drink plenty of water in order to get rid of harmful bacteria.

This way concentrated D-Mannose has more time to bind to E. coli bacteria before you flush them with water.

#2 Pricey mistake: Buying D-Mannose in capsules

Do not overpay by buying D-mannose capsules. You’ll not only be wasting your money but also ingesting all the extra ingredients that are required for processing the powder into capsules (for example rice flour, stearic acid, magnesium stearate and silica).

You can measure D-Mannose powder with a teaspoon, but don’t worry: you do not have to be precise.

The powder has a pleasant, sweet taste, and when you add D-Mannose to water, it dissolves easily.

#3 Dangerous mistake: Waiting too long before seeing a doctor

If you decided to treat your UTI with D-Mannose, know that you are assuming certain health risks, though they are not associated with D-Mannose itself.

The main side-effect risk is that D-Mannose won’t work for you and your UTI bacteria could ascend to your kidneys, which is a very serious infection.

Learn about main D-Mannose side effects and how to avoid them.

If your UTI symptoms have not diminished or completely disappeared after 1-2 days, do not wait any longer and go to the doctor.

Remember, D-Mannose only works for UTIs caused by E. coli bacteria, and if you let your infection go untreated, you are at risk of developing a dangerous kidney infection, or even deadly sepsis.

If you are experiencing frequent UTIs, there is a higher chance that your infections are caused by multiple bacteria types, not only E.coli.

Scientists still don’t know why for some suffering UTIs caused by E. coli, D-Mannose is a miracle cure, but for other patients, it simply doesn’t work.

One point to remember is that D-mannose is a natural product and it’s possible that variations in sources and methods of manufacture, as well as a diversity of pathogenic bacteria, could play a role.

#4 Taking D-Mannose too late

It appears that D-Mannose works best if taken preventively or at the very first signs of infection.

A full-blown UTI might benefit from D-Mannose supplementation, but you are running a risk that bacteria are growing at a faster rate than you are able to clear them.

If you end up taking antibiotics, supplementing with D-Mannose could be an option to speed up recovery, but do not stop your antibiotic treatment to switch to D-Mannose. You’ll be running a risk to develop a drug-resistant bacteria.

#5 Relying only on D-Mannose for your UTI treatment strategy

I understand your desire to stick with a natural supplementation for your UTI prevention and treatment needs.

However, UTIs (especially chronic ones) are a multi-faucet problem requiring a complex approach.

Thankfully, there are plenty of herbal and natural remedies to help you stay healthy!

If this is your first UTI, don’t wait for it to turn into a chronic problem. Contracting a UTI might be a warning signal from your body about other imbalances (vaginal flora, hormones, stones etc..).

#6 Buying D-Mannose made from corn if you are allergic to corn

Did you know that most of the D-Mannose products are made from corn? If you are allergic to corn, usual D-Mannose side-effects could be further exacerbated by your allergy reaction to D-Mannose (hives, GA troubles).

If you know or suspect that you might be allergic to corn, be sure to choose D-Mannose made from cranberries or pineapple.

D-Mannose Dose For Acute UTI

Consider this when trying to supplement your UTI treatment with D-mannose:

  1. Try the typical D-Mannose dose for UTI treatment: 1500-2000 mg (capsule form) or one-half to one teaspoon (powder) in a half glass of water every two to three hours for five days.
  2. Drink plenty of water in between D-Mannose doses.
  3. Remember that as of now, no one has clinically tested and established the exact quantity and frequency of D-Mannose for UTI treatment.
  4. Different people will react differently to the same D-Mannose dose (depending on their age, weight, overall health).
  5. The quality and purity of D-Mannose could vary from one manufacturing company to another, and even from one batch to another!
  6.  D-Mannose has certain side-effects and it’s important to weigh all pros and cons before you try it.
  7. Be careful which D-Mannose brand you chose if you are allergic to corn.
  8. Once you have started taking D-Mannose, UTI symptoms should significantly diminish within the first 48 hours, but keep it up for 2-3 more days even if the symptoms are gone. If your symptoms did not diminish within the first day, see a doctor immediately.
  9. Normally, one 50g dose (2-3 ounces) of D-Mannose is sufficient (most likely that’s how much you’d have in one package) for one course.
  10. Some find it beneficial to follow up an acute episode of a UTI with a month of preventive D-Mannose dose taken daily.
  11. Consult with your physician on how to supplement your UTI treatment with D-Mannose.

D-Mannose Dose For UTI Prevention

I take D-Mannose after certain trigger events that could cause my UTIs. Consider this when adding D-Mannose to your UTI prevention strategy:

  1. For UTI prevention take 1500-2000 mg (or one-half teaspoon) once or twice a day.
  2. You can take “preventive” dose safely for as long as you want. Your bacteria won’t develop a resistance.
  3. Ladies, take D-Mannose every time you think your vaginal flora is compromised (with the first signs of yeast infection, when consuming a lot of sugar, during stressful times, after sex, etc.).
  4. Check out my 8 Holistic Strategies to Prevent UTI Naturally here.

D-Mannose products: Best value for the buck

The more volume you buy, the less you pay!

Compare to:

Here are some more expensive D-Mannose brands that are not made from corn, and produced in the USA from cranberries and pineapples:

Read my full 2018 review of popular D-Mannose supplements that allows you to compare brands to understand which D-Mannose will last longer if you are taking it for prevention.

FAQs About D-Mannose & UTIs

Is D-Mannose suitable for children?

Well, at the end of the day, it is only a type of sugar—and not the harmful type! At the same time, the doses should be adapted according to age and weight. However, keep in mind that there is a rare genetic disease that messes up how this type of sugar (mannose) is produced and absorbed by your body. Make sure to educate yourself about it before treating yourself or your child.

Moreover, kids normally get UTIs because of urine retention or backward urine flow. It is important to diagnose them for the underlying issues causing the infection instead of trying to self-treat.

Definitely, do not use D-Mannose instead of antibiotics if kids are too young to report their symptoms. It is better to not experiment with any natural supplements and follow your doctor’s advice.

If your child is already taking an antibiotic, you can try to supplement it with D-Mannose. Be extra careful with the dosage, as too much can cause diarrhea.

Is D-Mannose suitable for diabetics?

D-Mannose is most likely suitable for diabetics. Since only very small amounts of D-Mannose are metabolized by the body, it won’t typically raise your sugar level.

Nonetheless, sugar levels in the blood should be monitored regularly. We still don’t know enough about D-mannose metabolism, so you should exercise caution.

How soon to expect a relief with D-Mannose?

If you started taking D-Mannose at the first signs of a UTI you would typically notice a drastic reduction in symptoms as soon as 24 to 48 hours. However, if you do not notice an improvement in your symptoms, make sure to see your physician right away.

An untreated UTI could turn into a dangerous kidney infection and even a lethal sepsis. Every time you choose to self-treat you are running a risk.

Moreover, D-Mannose supplements can also be taken for UTI prevention without damaging your natural digestive and vaginal flora, a benefit that antibiotics cannot provide.

D-Mannose and FDA: Important disclaimer

D-Mannose is a popular supplement among UTI sufferers who are looking for a natural solution to prevent and treat urinary tract infections (just scroll down the page to read comments from the readers like you!).

Anecdotal evidence is growing and contributing to the Internet hype about D-Mannose products since we all want to find a cure from UTI.

However, D-Mannose is a food supplement and FDA does not regulate it. A dietary supplement product is not able to claim it can be used to “diagnose, treat, cure or prevent any disease,” because only a drug can legally make such a claim. There is not enough scientific evidence that D-Mannose can treat a UTI, therefore, try it at your own risk and closely monitor your symptoms.

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  1. Hi thank you for your blog, i’m wondering if you can help me with a quick question:

    This is my first UTI in 30 years (i’m going through perimenopause) and i bought D Mannose powder and on advice of Naturopath, am taking 1 teaspoon 3 x a day. At first sign i started it and it gave me immediate relief of all symptoms (including peeing blood, no abdominal pain though) but now 2 days later the symptoms are back with a vengeance. Since i haven’t had one in years, should i go to walk in and just get antibiotics? THANKS

    • Hi Susie, if your symptoms are back, it would be wise to go for antibiotics. I’d recommend looking into your estrogen levels and take right probiotics once you clear the acute infection to prevent UTIs in the future. Best wishes,

  2. What dosing schedule do recommend for the Dmannose.
    The three day regimen: one teaspoon every two hours not to exceed 7 doses. Day 2 one teaspoon every three hours not to exceed 5 doses and the Day 3 one teaspoon every 4 hours not to exceed 3 doses.
    Are there other dosing suggestions?

    • Hello, there are no scientifically based doses, therefore I’d go either with the schedule recommended in this post (this is what most manufacturers suggest) or with the schedule that your doc/naturopath suggested. Frankly, if you take too much, the side-effects from the overdose are going to be pretty clear right away and you could just scale it down to keep diarrhea under the control.

  3. Hi I have enjoyed reading all of your comments. I have been trying from many Urologist about my Mom in whom she is older has dealt with this for many years.
    My doctor mentioned the Interstitial cystitic when I shared Moms story. And now I am reading about the D-Mannose. Also a comment about the Vit c cranberry pills and Doxycycline hyclate 100 ml. All great information. Best forum I have read.
    Remember to learn how the DN works with the e-coli attaching to bladder, pretty cool. My Doctor said that the New Azo for bladder pain, cranberry pill if you can’t drink Juice like my Mom, but 100 percent Juice. Kinda bitter. Then another key is good Probiotics Wiping properly and not to sound crude but if you have any e-coli and the man slips and re-enters the bacteria is then entroduced that way.
    All of you are so helpful!!! God bless you. Many elderly deal with constant UTI’s I hope a lot of caregivers see this.

  4. Hello, Anastasia! thank you for your blog, it helps me a lot and gives hope for recovery. Maybe you can give me an advise? I live in Russia, so buying d-mannose is hard for me, because it’s expensive and delivery takes more than 2 weeks. But that’s not really a problem if it helps, because i’ve been on anibiotics constantly for year and a half as I get UTI every time I have sex. I have also bacterial vaginosis (e-coli) and that’s the main reason. But till now I couldn’t cure it, cause I consumed antibiotics wich killed all of my good bacterias there. Now I use d-mannose and it works, BUT. Only in huge doses. And it gives me side effects (tramendous bloating), but I can deal with that for not consuming antibioics anymore.
    So, when I got my d-mannose powder I began to drink it every 3 hours for 5 days (I didn’t have an ongoing UTI, but had some constant discomfort in my bladder and while peeing). on 4th day I felt absolutly healthy. On weekends I had sex, and if on the first day I felt great (taking d-mannose rather often), in the end of second my discomfort returned. I didn’t get an acute form in the end, but I still can’t say that I’m great. Plus I spent the whole pack of now-foods d-mannose (6oz) in two weeks and I don’t know how I can use it more reasonable.
    I also regulary put lactobacterias into my vagina (every night), but I feel like I’m just trying to survive, not to heal completly. Maybe you have some advice on my case?

  5. Hi Anna, I stumbled accross your blog while desparately looking for a cure to end my UTI nightmare. Your selfless act makes me realize that I have so much to learn in uti and I am beyond thankul for your knowledge sharing. ???????????? Im taking probiotics now and want to incorporate d mannose in my diet. Should Intake d mannose and probitic together or have to stop Probiotic for now? Thank you.

  6. Hi, My 10yr old daughter has had tummy pains for 2 months, every day, below belly button very tender. We have tried a penicillin antibiotic to no avail, tried clearing her bowel in case an impaction. We realised the cramps get worse after acidic foods, OJ, ketchup, chocolate etc. 6 days ago she started to have bad urinary urgency. 3 days ago she started to get a burning sensation when peeing. I’m thinking it could be Interstitial Cystitis. I have been bringing her constantly to the doctors to get help, but they are not yet entertaining the idea that it could be IC. I’m going to drop in a pee and stool sample today to GP to send off for evaluation. We are at the start of day 3 of d mannose. I’m giving 1000mg doses. day 1 she got 4 doses 3 hrs apart, day 2 she got 5 doses 3 hrs apart. I’m thinking it’s making a difference, could be just wishful thinking. I’m also waiting on a delivery of Prelief to help alkalise the bladder. How do you rate d mannose for treating IC? Do you think the dose I’m giving is sufficient? The GP does not want to give an antibiotic until properly diagnosed. I and also waiting on a specialist appointment for her. I would be so grateful for your input on this matter, and any further suggestions for articles to read. AH

    • Hello AH,

      Poor girl! I hope you’ll get an answer soon. Here are couple things you could consider asking your physician for:
      -renal/bladder ultrasound to confirm that she is emptying her bladder properly
      -urine culture test to understand which bacteria are causing UTI-like symptoms
      Some things you could research further
      diet to help her bladder regardless whether this is IC or UTI. You can start eliminating some foods and see if it makes a difference in her symptoms
      -if your GP decides on any antibiotic treatment, see this and this post
      -you could ask your doc if anti-inflammatory tea/supplements are OK to try.

      It’s quite strange that her symptoms progressed from cramps to UTI-like symptoms. I wouldn’t take a liberty to provide a hypothesis on your IC suspicion, I think you are in good hands with the number of specialists you are seeing.:) My uneducated, non-medical guess would be about her UTI symptoms recently that, perhaps are not connected with her main complaint. It could be that penicillin treatment caused the decrease in her beneficial vaginal bacteria that led to colonization by pathogenic bacteria, they, in turn, ascended to the urinary tract causing a UTI. That’s why D-Mannose could be helping. Here is a quote from this study that has some relevance to effects of penicillin on vaginal microbiota
      “Penicillin administration was associated with an altered vaginal microbial community composition characterized by increased microbial diversity. Lactobacillus sp. contributed only 13.1% of the total community in the women that received penicillin compared to 88.1% in the controls. Streptococcus sp. were present in higher abundance in GBS positive woman compared to controls, with 60% of the total vaginal microbiota in severe cases identified as Streptococcus sp.”
      By the way, did she had any other health issues in the months prior to her first complaint on tummy pains? Is she, otherwise, a healthy girl or is there any other chronic issues? Make sure to thoroughly recall this information when seeing a urologist.
      Best wishes, and come back to share your progress. Hope she finds a relief from these troubles soon!

      • Thank you so much for your reply Anastasia, I shall ‘digest’ it all thoroughly! While she is a healthy, very tall for her age 10 year old, she did have a very hectic schedule in the 2 months before the pains materialised. After school activities and rehearsals for a 9 run theatre production. She never used to drink enough fluids, she would hold wee’s, and her teacher limited the class toilet trips. Also, we are on a self sufficient well water system that I now believe we didn’t monitor enough. It spiked again a month ago, after a nearby field was spread with slurry, (cow poo) to the point we couldn’t even bathe in it, and used bottled water until we sorted it, sanitised it, new filters etc. I then had our well water tested and it was fine. But that was a spike we noticed, maybe we didn’t notice ones before. We also have a ph leveler that feeds in to our water system as our water is naturally very acidic, and this was off line for a few months. I think it’s really hard to distinguish even a 10year olds description of cramps. I presumed it must be bowel. However the very first A&E doctor we saw, examined her and immediately said deep bladder infection, even though the urine dipstick was negative. I just thought it must be something else when the antibiotic did not work.
        I guess it’s a possibility thatmaybe some bladder infections enter vaginally, and others enter orally, so descend instead of ascend?

        • Hello AH 🙂
          To straighten things about how bacteria travel (applicable mostly to women), see this post, disregard the fact that this is about sex, bacteria travel the same way regardless.
          Mainly, there are two types of how bacteria can reach a bladder (if we exclude a procedure or surgery): blood born – that’s very rare and comes with systemic infection would be probably only applicable if you have some sort of immune deficit disease (but I could be wrong) and by ascending from the perianal area. Opportunistic bacteria cohabitate peacefully in your lower intestines at all times, you don’t need to contract them from the outside world to get a UTI. So whatever you’ll put in your mouth will be digested in your stomach, then goes to your intestines, travels toward lower intestines and waste comes out when you poop. No matter how clean she is, a microscopic amount of poop is always there 🙂 If her vaginal flora is healthy, it’ll deter any bad bacteria from traveling up. That’s why probiotics are so good to take after (or even during) antibiotic treatment. It’s actually the best practice in many European countries.
          To be honest, maybe just try (consult with your doc first) some anti-inflammatory options (ranging from NSAIDs to Cornsilk tea, Marshmallow root tea etc..). Even just something relaxing like chamomile tea before she goes to bed. I’m puzzled why would you get antibiotics given that her only complaint was lower abdomen pain. Perhaps. her urine analysis showed significant bacterial overgrowth? Can you just take a look at the results of her urine tests? That would shed some light on the issue.

        • Meant to say enter via *urethra. Doh! I am trying to think of all possibilities. BTW, since day 3 of D mannose the cramping pain that was there everyday for 2 months has gone. Cutting out acidic foods has helped too. We’ll get there.

  7. I have used D-Mannose successfully for many years, both powder and pills. For me, D-Mannose is better as a prevention than a cure. The first time I used it I purchased the powder from The Vitamin Shoppe (Kal-D Mannose 2.5 oz $31.99) and my symptoms were “very early.” The next day it was completely gone and I was sold on D-Mannose. The second time I was well into my symptoms and after taking the supplement (I ordered the capsules from Amazon: Harmony D-Mannose $29.99) it did not go away and I ended up going to the doctor to get antibiotics. I began using the powder as a prevention twice daily and was infection free for many months. I think you have to get enough of the D-Mannose in your system for it to work its magic. Those who suffer from frequent UTIs know when one is about to come on. That’s the time to take the D-Mannose. Also, for women, AFTER SEX take a dose. I also have to agree the powder is much cheaper to use than the pills.

    • My UTI fix in a combination of three items.
      1. High Vitamin C, I take ~ 1,500 mg daily – easy and inexpensive
      2. AZO cranberry pills, 2 a day is considered one serving – easy and not expensive
      3. A antibiotic called Doxycycline hyclate 100 mg caps. I take just one every ~ 3 days. Easy.
      The idea is incoming germs have to mutate three different ways to grow in my bladder. After 2 years
      of getting unending UTI’s, this program stopped it. Now two years and no UTI. I was under the treatment of 3 different
      Urologist and just getting different antibiotics that worked for a while but they were losing their strength.
      I was in a terminal condition. That’s it.

  8. hello Anastasia
    I was 39 years old healthy man before I got UTI caused by E. coli. Several times I have used antibiotics prescribed by different doctors ( 4 times already). no result, it continues again and again already 6 months. after every antibiotic treatment I get better, but about one month later starts new wave of infection. I already don’t know what to do. I will definitely try D-Mannose. Could you give me advise what else can I do with my infection?
    thank you in advace

    • Hello Irakli, sorry to hear, sounds like e.coli causing lots of trouble. Here is a post specific to guys & UTI. I assume, you have seen a urologist and they checked your prostate, bladder, and kidneys? How’s your immune system? Any other health issues that you have been experiencing before you started having your infections? Most likely, your doctor told you to start using condoms, are you following this suggestion? So to just clarify, first you want to establish the source of the infection and fix that.
      In terms of UTI supplements, for starters, check out the links that I just posted in my previous reply, but most importantly, educate yourself about bacterial biofilms. Unfortunately, UTI in men are always considered complicated and there might be some underlying infections that have to be treated, so antibiotics could be an inevitable part of the program, but you can definitely check with your doctor if taking NAC would improve your chances.
      Best of luck, I hope you’ll be able to take it under control

  9. Hi. I’m reading all the information on your page and all the reviews too. My daughter who is now 15 has been suffering with UTIs since she was 5. Possibly before 5 as she used to cry in pain so much when she was younger and get so cross but looking back now I’m sure it was the UTI. She used to say”mummy it tickles” and hold herself and cry at age 4.
    So she’s had every test at the hospital several times over and each time they say she will grow out of it and give her more preventative antibiotics. She’s been on preventative treatments for years until we decided to stop them last year as I was worried about her taking them long term. More than 10 years! She previously took nitrofuantoin, trimethoprim, co amaxiav I’m sure she’s become resistant to all of them.
    Since coming off the preventatives she’s been happier in her self but does get infections still. Just taking antibiotics for a treatment for a week until it’s gone.
    I’ve been searching for something else natural to try.
    After recently suffering from a terribly painfull infection myself and realising again how much pain my daughter goes through with UTIs I wanted to find something else to help. I brought 500mg capsules from amazon. I REALLY hope they work for her
    It states 3x 500mg capsules 3x per day. Do you think this is for treatment or prevention?
    Also can you let me know what the powder tastes like?? We may need to buy in bulk if this works. I really hope it does!


  10. Hi, I have just begun taking d-mannose capsules ( I will get the powder next time) . I have been paralyzed for 10 months now and have had recurrent UTIs. I am currently on macrobid and have been on antibiotics almost Non-Stop but I keep getting a UTI. So I’m hoping this works! ..I’d like to go back about 11 months and I was being treated for a UTI and can’t remember which type of antibiotic I was on however a short time later I began having leg and back discomfort. Within a month I was paralyzed from my waist down. Now I’m not saying it was the antibiotics but somehow I was diagnosed with idiopathic transverse myelitis which means they don’t know what caused it ( it wasn’t a disease ) & I did recently read that some types of antibiotics cause immune system issues and that’s exactly what transverse myelitis is but in a more intensive form. At any rate I thought everyone should give d-mannose a try before using antibiotics.

    • Hi Bonny, thank you for sharing your story. You sound like a fighter!
      D-Mannose is a good supplement, but please also check this post about bacterial biofilms especially if you have been using a catheter. You can ask your doctor if it would be safe for you to take, for example, NAC together with Macrobid.
      I can’t even imagine how much you have researched about your case of paralysis by now, sorry I can’t really help in any way, but I thought about this Ted Talk since I like this woman’s perspective on the importance of microelement deficiency, which probably applies to all of us to a certain extent.
      Best wishes and warm regards,

    • hi your issue sounds like it could have been caused by cipro, an antibiotic commonly prescribed. there is a term as floxed look it up and see if you can relate. many people including myself have been damaged by this antibiotic.

  11. Hi
    I bought nature’s answer UT ANSWER.When I saw the instructions it says day 1: 4 servings,day 2: 2 servings,day 3: 2 servings
    One serving is 15ml

    So do I need to take 4 servings at a time or I can spread and take 15ml 4 times on day one ?

    • Hello!
      It has a generous portion of D-Mannose per serving. Depending what are you trying to do? If I was attempting to supplement with it during an active infection, I would take 1/2 of the dose but more often, every three hours or so. But the manufacturer must have good reasons to suggest their protocol.

  12. I have an E. coli infection. I did cranberry juice for several weeks and maybe o I have E. coli infection. I did cranberry juice for several weeks and it went away. It came back again so I took the medication the doctor prescribed an antibiotic. Three hours after taking I was paralyzed. I couldn’t move any part of my body from my eyes to my toes. When I was finally able to move again I called my Doctor Who said antibiotics don’t work for E. coli symptoms. But, here’s another antibiotic to try. When I looked up the first anabiotic it’s said do not use this for E. coli infections. So, I purchased a d-mannose. Within a couple days the symptoms have gone away. Any thoughts on antibiotics And e coli infections?


    • Hi Roger,
      Sorry to hear about your troubles. Do you remember the name of the antibiotic you tried and that caused such bad side-effects?
      Most of UTIs are caused by E.coli and are successfully treated with an antibiotic, there is a range of drugs that could be used. Perhaps, he ran a lab test to establish the sensitivity of your particular strain of bacteria to that particular type of antibiotic and it was resistant? That would be my only explanation.


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